Monthly Archives: September 2009

Editor’s and Fellows’ Journal Club Choices, September 2009

Editor’s Choices

Intelligence and Medial Temporal Lobe Function in Older Adults: A Functional MR Imaging-Based Investigation • D.M. Yousem, M.A. Yassa, C. Cristinzio, I. Kusevic, M. Mohamed, B.S. Caffo, and S.S. Bassett
In this interesting prospective study, the influence of intelligence and education on cortical activation of the temporal lobes was studied. The authors recruited 38 adults and subjected them to auditory paradigms thought to activate the medial temporal lobes. Results of fMRI were then correlated with IQs and educational levels (assuming there is a relationship between both). All subjects had normal IQs and time spent in education varied widely. … Continue reading >>

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Aunt Mickey (They Look the Same until You Undress Them). Meningioma or Something Else?

A young African American woman presented with progressive left vision loss.  Brain MRI with contrast and perfusion studies were obtained.  The studies showed a dural-based lesion involving the lateral aspect of the left cavernous sinus which extended superiorly and crossed the planum sphenoidale to insinuate itself around the contralateral anterior clinoid process. The lesion was isointense to gray matter on T1WI, dark on T2WI, showed homogeneous gadolinium enhancement and increased rCBV on the perfusion images (see below).  The provisional diagnosis of meningioma was made and the patient scheduled for surgical decompression of left optic canal.

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Before surgery, a chest radiograph … Continue reading >>

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Ischemia and Loss of Vascular Autoregulation in Ocular and Cerebral Disease: A New Perspective

Ischemia and Loss of Vascular Autoregulation in Ocular and Cerebral Disease: A New Perspective.
M.E. Langham. Springer; 2009, 192 pages, 94 illustrations, $99.00.

Maurice E. Langham’s Ischemia and Loss of Vascular Autoregulation in Ocular and Cerebral Diseases: A New Perspective summarizes a life’s work dedicated to understanding how a complex interaction of factors, such as intraocular pressures, ocular perfusion, and autoregulation affect ocular health. As such, this sole-authored text explores the subtle nuances of highly sophisticated instrumentation used to determine these factors that will exceed the needs or interests of most practicing ophthalmologists and neuroradiologists.

The book is divided into … Continue reading >>

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Educational Presentation: Congenital Anomalies of the Pituitary Gland

Congenital Pituitary Abns (NXPowerLite)

Here is the third on my series of educational presentations.  It deals with embryology, anatomy and congenital abnormalities of the pituitary gland.  I need to acknowledge that this one was authored by Drs. Spampinato, Camacho and Grimme during their fellowships here at UNC and was previously shown at ASNR.  Like the other two presentations, it is compressed and it is not protected so please give credit to its source if you decide to use it for teaching purposes elsewhere.… Continue reading >>

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Aunt Mickey (They Look the Same until You Undress Them). Myxopapillary Ependymoma or Something Else?

This young male presented with chronic but progressive low back pain and lower extremity weakness.  MR imaging of the lumbar spine with contrast showed a lesion, intradural/extramedullary, extending from T12 to L4.  The lesion “expanded” the spinal canal and produced significant remodeling (scalloping) of the posterior vertebral bodies.  The mass had mostly low T1 signal pre contrast, mostly high T2 signal and enhanced after gadolinium.  Is it a large myxopapillary ependymoma?

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Analysis of axial images showed that the mass involved the spinal canal but extended out into the paraspinal regions, including the right psoas muscle, via several neural foramina.  The … Continue reading >>

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