Editor’s Choices for May 2015

Krings T, Kim H, Power S, et al. Neurovascular Manifestations in Hereditary Hemorrhagic Telangiectasia: Imaging Features and Genotype-Phenotype Correlations. http://www.ajnr.org/content/36/5/863.full

Imaging features were correlated with genotypes in 75 patients with hereditary hemorrhagic telangiectasia. Sixty-one percent of patients showed small, superficial, capillary malformations without shunting, whereas 43% had true AVMs of small size and low Spetzler-Martin grade. High-flow AVFs were present in 12% of patients and multiple malformations were seen in 44%. No correlation between gene mutations and lesion types was found.

Golden MJ, Morrison LA, Kim H, et al. Increased Number of White Matter Lesions in Patients with Familial Cerebral Cavernous Malformations. http://www.ajnr.org/content/36/5/899.full

Because endothelial cell abnormalities are found in white matter hyperintensities and cavernous malformations, the authors set out to determine if an increased number of white matter lesions was present in 191 patients with familial cerebral cavernous malformations all carrying the same gene defect. Results were compared with those obtained via logistic regression analysis in healthy controls and patients with sporadic cavernous malformations. White matter lesions were found in 15% of patients with the familial disease, 2% of healthy controls, and 2.5% of those with sporadic malformations. In patients with the familial disease, only age was associated with white matter lesions.

Cho CH, Hsu L, Ferrone ML, et al. Validation of Multisociety Combined Task Force Definitions of Abnormal Disk Morphology. http://www.ajnr.org/content/36/5/1008.full

Fifty-four patients underwent classification of lumbar disk herniations during preoperative MRI and surgery using the new multisociety classification. Disagreement as to classification based on MRI studies occurred in only 1 instance and agreement of preoperative classification with operative findings was 70%. The authors believe that though this level of agreement is reasonable, differences exist between what neuroradiologists see on imaging and what surgeons encounter.

Editor’s Choices for May 2015
Mauricio Castillo • Univ of North Carolina

I am Division Chief of Neuroradiology at the University of North Carolina in Chapel Hill. In addition, I am a Professor of Radiology and the current Editor-in-Chief of the American Journal of Neuroradiology. I trained in Diagnostic Radiology at the University of Miami and was a Neuroradiology fellow at Emory University.