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Author Archives: Paresh Desai
Familial Multiple Cavernous Angiomas: Screening of a Family Over Three Generations
INTRODUCTION
Cavernous angiomas belong to a group of intracranial vascular malformations that are developmental malformations of the vascular bed. These congenital abnormal vascular connections frequently enlarge over time. The lesions can occur on a familial basis. Patients may be asymptomatic, although they often present with headaches, seizures, or small parenchymal hemorrhages.
In most patients cavernous angiomas are solitary and asymptomatic. In recent times, increasing MR imaging has detected several such asymptomatic cases and has prompted a study into the genetics and natural history of this condition.
It is now known that cavernous angiomas have a genetic basis. Familial forms … Continue reading >>
Posted in Brain
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How to report Transient Splenial Lesion and How Often to Follow It Up?
A 39-year-old man with history of tingling sensation on the left half of Face.
MRI revealed a solitary lesion in the splenium of the corpus callosum, hyperintense on T2/FLAIR and hypointense on T1W images. There is diffusion restriction.
This lesion was presumed demyelinating in view of h/o upper respiratory tract infection. At 6-week follow up MRI the lesion resolved completely.
Various etiologies have been reported for transient splenial lesions like:
- Seizures
- Sudden withdrawal of antiepileptic drugs
- Brain infarction
- Multiple sclerosis
- Cerebral trauma
- Neoplasm
- Adrenoleukodystrophy
- AIDS dementia complex
- Infections like influenza, measles, herpes, Salmonella, mumps, adenovirus, varicella zoster, Legionnaires disease,
Posted in Brain, Uncategorized
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