Author Archives: Sotirios Bisdas

In the recent paper of Kim et al. [1], the authors attempt for first time to examine the relationship between pharmacokinetic parameters, obtained by dynamic contrast-enhanced (DCE)-MRI, of a metastatic target node and treatment outcome in patients with neck cancer. The paper makes 3 important contributions to the DCE neck imaging: 1) adding to the evidence gained by Cao et al. [2], Kim et al. derived (based on a two-compartment pharmacokinetic model) quantitative perfusion-associated parameters 2) similarly to the work of Bisdas et al. [3] microcirculation parameters (other to blood flow, blood volume, and permeability) such as Ktrans (transfer constant), … Continue reading >>