Tag Archives: DTI

ADC Question

I will like to know if someone can help me with some doubts I have regarding ADCs.

1.  I have  a sample with some ADC values obtained in 1,5 T and others obtained in 3T ( same b value). Can I use the ADC values for statistics or do you think that they cannot be compared?

2.  Are the ADC values obtained using a diffusion sequence  the same that the ADC values obtained in a DTI sequence with 12 directions?

Thank you in advance.… Continue reading >>

Posted in Brain, Functional | Tagged , , | 1 Comment

Using DTI-MRI in Geron’s Phase I Clinical Trial

What do you think about the use of DTI-MRI for tracking the progress of therapy in Geron’s upcoming Phase I clinical trial? DTI measures (transverse and longitudinal diffusivity) in some rodent models of spinal cord injury have shown correlations with myelination and axonal integrity. If the intraspinally injected oligodendrocyte progenitor cells are indeed remyelinating damaged axons, then perhaps tracking patients with non-invasive DTI-MRI could allow the investigators to better assess the outcomes of their intervention?… Continue reading >>

Posted in Spine | Tagged , , | Leave a comment