AJNR Blog » DTI http://www.ajnrblog.org American Journal of Neuroradiology Wed, 01 Feb 2012 21:10:26 +0000 en hourly 1 ADC Question http://www.ajnrblog.org/2009/03/24/adc-question/ http://www.ajnrblog.org/2009/03/24/adc-question/#comments Tue, 24 Mar 2009 22:32:12 +0000 nbargallo http://www.ajnrblog.org/?p=729 I will like to know if someone can help me with some doubts I have regarding ADCs.

1.  I have  a sample with some ADC values obtained in 1,5 T and others obtained in 3T ( same b value). Can I use the ADC values for statistics or do you think that they cannot be compared?

2.  Are the ADC values obtained using a diffusion sequence  the same that the ADC values obtained in a DTI sequence with 12 directions?

Thank you in advance.… Continue reading >>

]]> I will like to know if someone can help me with some doubts I have regarding ADCs.

1.  I have  a sample with some ADC values obtained in 1,5 T and others obtained in 3T ( same b value). Can I use the ADC values for statistics or do you think that they cannot be compared?

2.  Are the ADC values obtained using a diffusion sequence  the same that the ADC values obtained in a DTI sequence with 12 directions?

Thank you in advance.

]]> http://www.ajnrblog.org/2009/03/24/adc-question/feed/ 1 Using DTI-MRI in Geron’s Phase I Clinical Trial http://www.ajnrblog.org/2009/02/09/using-dti-mri-in-gerons-phase-i-clinical-trial/ http://www.ajnrblog.org/2009/02/09/using-dti-mri-in-gerons-phase-i-clinical-trial/#comments Mon, 09 Feb 2009 19:52:58 +0000 cpatel http://www.ajnrblog.org/?p=446 What do you think about the use of DTI-MRI for tracking the progress of therapy in Geron’s upcoming Phase I clinical trial? DTI measures (transverse and longitudinal diffusivity) in some rodent models of spinal cord injury have shown correlations with myelination and axonal integrity. If the intraspinally injected oligodendrocyte progenitor cells are indeed remyelinating damaged axons, then perhaps tracking patients with non-invasive DTI-MRI could allow the investigators to better assess the outcomes of their intervention?… Continue reading >>

]]> What do you think about the use of DTI-MRI for tracking the progress of therapy in Geron’s upcoming Phase I clinical trial? DTI measures (transverse and longitudinal diffusivity) in some rodent models of spinal cord injury have shown correlations with myelination and axonal integrity. If the intraspinally injected oligodendrocyte progenitor cells are indeed remyelinating damaged axons, then perhaps tracking patients with non-invasive DTI-MRI could allow the investigators to better assess the outcomes of their intervention?

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